Publikationen
2024
D.
Geist,
G. S.
Hones,
S. C.
Grund,
J.
Pape,
D.
Siemes,
P.
Spangenberg,
E.
Tolstik,
S.
Dorr,
N.
Spielmann,
H.
Fuchs,
V.
Gailus-Durner,
M.
Angelis,
J.
Mittag,
D. R.
Engel,
D.
Fuhrer,
K.
Lorenz, and
L. C.
Moeller,
Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice, Thyroid , 2024.
Canonical and noncanonical contribution of thyroid hormone receptor isoforms alpha and beta to cardiac hypertrophy and heart rate in male mice, Thyroid , 2024.
| DOI: | 10.1089/thy.2023.0683 |
| Datei: | 38757582 |
A. M.
Naujack,
C.
Krause,
J. H.
Britsemmer,
N.
Taege,
J.
Mittag, and
H.
Kirchner,
Epigenetic regulation of thyroid hormone action in human metabolic dysfunction associated steatohepatitis, Eur Thyroid J , 2024.
Epigenetic regulation of thyroid hormone action in human metabolic dysfunction associated steatohepatitis, Eur Thyroid J , 2024.
| DOI: | 10.1530/ETJ-24-0080 |
| Datei: | 39189972 |
S. C.
Sentis,
R.
Dore,
R.
Oelkrug,
B.
Kolms,
K. A.
Iwen, and
J.
Mittag,
Hypothalamic Thyroid Hormone Receptor alpha1 Signaling Controls Body Temperature, Thyroid , 2024.
Hypothalamic Thyroid Hormone Receptor alpha1 Signaling Controls Body Temperature, Thyroid , 2024.
| DOI: | 10.1089/thy.2023.0513 |
| Datei: | 38149585 |
J.
Maier,
R.
Dore,
R.
Oelkrug,
A.
Glatzel,
A. L.
Cremer,
S.
Binder,
M.
Schwaninger,
H.
Oster,
H.
Backes, and
J.
Mittag,
Inhibition of Thyroid Hormone Signaling in the Zona Incerta Alters Basal Metabolic Rate, Behavior and Serum Glucocorticoids in Male Mice, Thyroid , 2024.
Inhibition of Thyroid Hormone Signaling in the Zona Incerta Alters Basal Metabolic Rate, Behavior and Serum Glucocorticoids in Male Mice, Thyroid , 2024.
| DOI: | 10.1089/thy.2024.0209 |
| Datei: | 39189416 |
R.
Dore,
S. C.
Sentis,
K.
Johann,
N.
Lopez Alcantara,
J.
Resch,
A.
Chandrasekar,
H.
Muller-Fielitz,
L. C.
Moeller,
D.
Fuhrer,
M.
Schwaninger,
B.
Obermayer,
R.
Opitz, and
J.
Mittag,
Partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy in mice lacking thyroid hormone receptor beta, Thyroid , 2024.
Partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy in mice lacking thyroid hormone receptor beta, Thyroid , 2024.
| DOI: | 10.1089/thy.2023.0638 |
| Datei: | 38526409 |
S.
Asaad,
T. S.
Chillon,
D.
Filipowicz,
B.
Wilms,
F.
Strenge,
E.
Szczepanek-Parulska,
W. B.
Minich,
S. M.
Meyhofer,
J. U.
Marquardt,
J.
Mittag,
H.
Oster,
M.
Ruchala, and
L.
Schomburg,
Serum CD5L as potential biomarker of thyroid hormone status during pregnancy, Biofactors , 2024.
Serum CD5L as potential biomarker of thyroid hormone status during pregnancy, Biofactors , 2024.
| DOI: | 10.1002/biof.2123 |
| Datei: | 39345206 |
R.
Dore, and
J.
Mittag,
Thyroid Hormone Receptors in Control of Heart Rate, Endocrinology , vol. 165, no. 9, 2024.
Thyroid Hormone Receptors in Control of Heart Rate, Endocrinology , vol. 165, no. 9, 2024.
| DOI: | 10.1210/endocr/bqae093 |
| Datei: | 39047059 |
L. V. M.
Assis,
L.
Harder,
J. T.
Lacerda,
R.
Parsons,
M.
Kaehler,
I.
Cascorbi,
I.
Nagel,
O.
Rawashdeh,
J.
Mittag, and
H.
Oster,
Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice, Sci Rep , vol. 14, no. 1, pp. 640, 2024.
Tuning of liver circadian transcriptome rhythms by thyroid hormone state in male mice, Sci Rep , vol. 14, no. 1, pp. 640, 2024.
| DOI: | 10.1038/s41598-023-50374-z |
| Datei: | 38182610 |
H.
Kerp,
J.
Gassen,
S. C.
Grund,
G. S.
Hones,
S.
Dorr,
J.
Mittag,
N.
Harting,
F.
Kaiser,
L. C.
Moeller,
K.
Lorenz, and
D.
Fuhrer,
Cardiac recovery from pressure overload is not altered by thyroid hormone status in old mice, Front Endocrinol (Lausanne) , vol. 15, pp. 1339741, 2024.
Cardiac recovery from pressure overload is not altered by thyroid hormone status in old mice, Front Endocrinol (Lausanne) , vol. 15, pp. 1339741, 2024.
| DOI: | 10.3389/fendo.2024.1339741 |
| Datei: | 38455657 |
2023
V. K. A.
Sreenivasan,
R.
Dore,
J.
Resch,
J.
Maier,
C.
Dietrich,
J.
Henck,
S.
Balachandran,
J.
Mittag, and
M.
Spielmann,
Single-cell RNA-based phenotyping reveals a pivotal role of thyroid hormone receptor alpha for hypothalamic development, Development , vol. 150, no. 3, 2023.
Single-cell RNA-based phenotyping reveals a pivotal role of thyroid hormone receptor alpha for hypothalamic development, Development , vol. 150, no. 3, 2023.
| DOI: | 10.1242/dev.201228 |
| Datei: | 36715020 |
L.
Roth,
K.
Johann,
G. S.
Hones,
R.
Oelkrug,
L.
Wagner,
A.
Hoffmann,
K.
Krohn,
L. C.
Moeller,
J.
Weiner,
J. T.
Heiker,
N.
Kloting,
A.
Tönjes,
M.
Stumvoll,
M.
Blüher,
J.
Mittag, and
K.
Krause,
Thyroid hormones regulate Zfp423 expression in regionally distinct adipose depots through direct and cell-autonomous action, Cell Rep , vol. 42, no. 2, pp. 112088, 2023.
Thyroid hormones regulate Zfp423 expression in regionally distinct adipose depots through direct and cell-autonomous action, Cell Rep , vol. 42, no. 2, pp. 112088, 2023.
| DOI: | 10.1016/j.celrep.2023.112088 |
| Datei: | 36753417 |
R.
Dore,
L.
Watson,
S.
Hollidge,
C.
Krause,
S. C.
Sentis,
R.
Oelkrug,
C.
Geissler,
K.
Johann,
M.
Pedaran,
G.
Lyons,
N.
Lopez-Alcantara,
J.
Resch,
F.
Sayk,
K. A.
Iwen,
A.
Franke,
T. J.
Boysen,
J. W.
Dalley,
K.
Lorenz,
C.
Moran,
K. L.
Rennie,
A.
Arner,
H.
Kirchner,
K.
Chatterjee, and
J.
Mittag,
Resistance to thyroid hormone induced tachycardia in RTHalpha syndrome, Nat Commun , vol. 14, no. 1, pp. 3312, 2023.
Resistance to thyroid hormone induced tachycardia in RTHalpha syndrome, Nat Commun , vol. 14, no. 1, pp. 3312, 2023.
| DOI: | 10.1038/s41467-023-38960-1 |
| Datei: | 37286550 |
N.
Lopez-Alcantara,
R.
Oelkrug,
S. C.
Sentis,
H.
Kirchner, and
J.
Mittag,
Lack of thyroid hormone receptor beta is not detrimental for non-alcoholic steatohepatitis progression, iScience , vol. 26, no. 10, pp. 108064, 2023.
Lack of thyroid hormone receptor beta is not detrimental for non-alcoholic steatohepatitis progression, iScience , vol. 26, no. 10, pp. 108064, 2023.
| DOI: | 10.1016/j.isci.2023.108064 |
| Datei: | 37822510 |
R.
Oelkrug,
L.
Harder,
M.
Pedaran,
A.
Hoffmann,
B.
Kolms,
J.
Inderhees,
S.
Gachkar,
J.
Resch,
K.
Johann,
O.
Johren,
K.
Krause, and
J.
Mittag,
Maternal thyroid hormone receptor beta activation in mice sparks brown fat thermogenesis in the offspring, Nat Commun , vol. 14, no. 1, pp. 6742, 2023.
Maternal thyroid hormone receptor beta activation in mice sparks brown fat thermogenesis in the offspring, Nat Commun , vol. 14, no. 1, pp. 6742, 2023.
| DOI: | 10.1038/s41467-023-42425-w |
| Datei: | 37875497 |
2022
S. M.
Sundaram,
A.
Arrulo Pereira,
H.
Muller-Fielitz,
H.
Kopke,
M.
De Angelis,
T. D.
Muller,
H.
Heuer,
J.
Korbelin,
M.
Krohn,
J.
Mittag,
R.
Nogueiras,
V.
Prevot, and
M.
Schwaninger,
Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency, Brain , 2022.
Gene therapy targeting the blood-brain barrier improves neurological symptoms in a model of genetic MCT8 deficiency, Brain , 2022.
| DOI: | 10.1093/brain/awac243 |
| Datei: | 35929549 |
L. V. M.
Assis,
L.
Harder,
J. T.
Lacerda,
R.
Parsons,
M.
Kaehler,
I.
Cascorbi,
I.
Nagel,
O.
Rawashdeh,
J.
Mittag, and
H.
Oster,
Rewiring of liver diurnal transcriptome rhythms by triiodothyronine (T3) supplementation, Elife , vol. 11, 2022.
Rewiring of liver diurnal transcriptome rhythms by triiodothyronine (T3) supplementation, Elife , vol. 11, 2022.
| DOI: | 10.7554/eLife.79405 |
| Datei: | 35894384 |
E.
Rial-Pensado,
V.
Rivas-Limeres,
C.
Grijota-Martinez,
A.
Rodriguez-Diaz,
V.
Capelli,
O.
Barca-Mayo,
R.
Nogueiras,
J.
Mittag,
C.
Dieguez, and
M.
Lopez,
Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis, Front Physiol , vol. 13, pp. 1017381, 2022.
Temperature modulates systemic and central actions of thyroid hormones on BAT thermogenesis, Front Physiol , vol. 13, pp. 1017381, 2022.
| DOI: | 10.3389/fphys.2022.1017381 |
| Datei: | 36467699 |
R.
Oelkrug, and
J.
Mittag,
Too much too soon - Tissue-specific inactivation of deiodinase type 3 prematurely exposes brown fat to thyroid hormone, Endocrinology , 2022.
Too much too soon - Tissue-specific inactivation of deiodinase type 3 prematurely exposes brown fat to thyroid hormone, Endocrinology , 2022.
| DOI: | 10.1210/endocr/bqac032 |
| Datei: | 35294005 |
G. S.
Hones,
N.
Harting,
J.
Mittag, and
F. J.
Kaiser,
TRalpha2-An Untuned Second Fiddle or Fine-Tuning Thyroid Hormone Action?, Int J Mol Sci , vol. 23, no. 13, 2022.
TRalpha2-An Untuned Second Fiddle or Fine-Tuning Thyroid Hormone Action?, Int J Mol Sci , vol. 23, no. 13, 2022.
| DOI: | 10.3390/ijms23136998 |
| Datei: | 35806002 |
2021
V.
Capelli,
C.
Grijota-Martinez,
N. R. V.
Dragano,
E.
Rial-Pensado,
J.
Ferno,
R.
Nogueiras,
J.
Mittag,
C.
Dieguez, and
M.
Lopez,
Orally Induced Hyperthyroidism Regulates Hypothalamic AMP-Activated Protein Kinase, Nutrients , vol. 13, no. 12, 2021.
Orally Induced Hyperthyroidism Regulates Hypothalamic AMP-Activated Protein Kinase, Nutrients , vol. 13, no. 12, 2021.
| DOI: | 10.3390/nu13124204 |
| Datei: | 34959756 |
V.
Capelli,
C.
Dieguez,
J.
Mittag, and
M.
Lopez,
Thyroid wars: the rise of central actions, Trends Endocrinol Metab , 2021.
Thyroid wars: the rise of central actions, Trends Endocrinol Metab , 2021.
| DOI: | 10.1016/j.tem.2021.05.006 |
| Datei: | 34294513 |
E.
Milbank,
N. R. V.
Dragano,
I.
Gonzalez-Garcia,
M. R.
Garcia,
V.
Rivas-Limeres,
L.
Perdomo,
G.
Hilairet,
F.
Ruiz-Pino,
P.
Mallegol,
D. A.
Morgan,
R.
Iglesias-Rey,
C.
Contreras,
L.
Vergori,
J.
Cunarro,
B.
Porteiro,
A.
Gavalda-Navarro,
R.
Oelkrug,
A.
Vidal,
J.
Roa,
T.
Sobrino,
F.
Villarroya,
C.
Dieguez,
R.
Nogueiras,
C.
Garcia-Caceres,
M.
Tena-Sempere,
J.
Mittag,
M.
Carmen Martinez,
K.
Rahmouni,
R.
Andriantsitohaina, and
M.
Lopez,
Small extracellular vesicle-mediated targeting of hypothalamic AMPKalpha1 corrects obesity through BAT activation, Nat Metab , vol. 3, no. 10, pp. 1415-1431, 2021.
Small extracellular vesicle-mediated targeting of hypothalamic AMPKalpha1 corrects obesity through BAT activation, Nat Metab , vol. 3, no. 10, pp. 1415-1431, 2021.
| DOI: | 10.1038/s42255-021-00467-8 |
| Datei: | 34675439 |
S. C.
Sentis,
R.
Oelkrug, and
J.
Mittag,
Thyroid hormones in the regulation of brown adipose tissue thermogenesis, Endocr Connect , vol. 10, no. 2, pp. R106-R115, 2021.
Thyroid hormones in the regulation of brown adipose tissue thermogenesis, Endocr Connect , vol. 10, no. 2, pp. R106-R115, 2021.
| DOI: | 10.1530/EC-20-0562 |
| Datei: | 33491659 |
M.
Pedaran,
R.
Oelkrug,
Q.
Sun,
J.
Resch,
L.
Schomburg, and
J.
Mittag,
Maternal thyroid hormone programs cardiovascular functions in the offspring, Thyroid , 2021.
Maternal thyroid hormone programs cardiovascular functions in the offspring, Thyroid , 2021.
| DOI: | 10.1089/thy.2021.0275 |
| Datei: | 34269617 |
J.
Weiner,
L.
Roth,
M.
Kranz,
P.
Brust,
A.
Boelen,
N.
Kloting,
J. T.
Heiker,
M.
Blüher,
A.
Tönjes,
P. T.
Pfluger,
M.
Stumvoll,
J.
Mittag, and
K.
Krause,
Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels, Mol Metab , vol. 54, pp. 101348, 2021.
Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels, Mol Metab , vol. 54, pp. 101348, 2021.
| DOI: | 10.1016/j.molmet.2021.101348 |
| Datei: | 34610354 |
Z. M.
Li,
M.
Miller,
S.
Gachkar,
J.
Mittag,
S. C.
Schriever,
P. T.
Pfluger,
K. W.
Schramm, and
M.
De Angelis,
Determination of 3-iodothyronamine (3-T1AM) in mouse liver using liquid chromatography-tandem mass spectrometry, J Chromatogr B Analyt Technol Biomed Life Sci , vol. 1165, pp. 122553, 2021.
Determination of 3-iodothyronamine (3-T1AM) in mouse liver using liquid chromatography-tandem mass spectrometry, J Chromatogr B Analyt Technol Biomed Life Sci , vol. 1165, pp. 122553, 2021.
| DOI: | 10.1016/j.jchromb.2021.122553 |
| Datei: | 33503577 |
R.
Oelkrug, and
J.
Mittag,
An improved method for the precise unravelment of non-shivering brown fat thermokinetics, Sci Rep , vol. 11, no. 1, pp. 4799, 2021.
An improved method for the precise unravelment of non-shivering brown fat thermokinetics, Sci Rep , vol. 11, no. 1, pp. 4799, 2021.
| DOI: | 10.1038/s41598-021-84200-1 |
| Datei: | 33637831 |
2020
S.
Nock,
K.
Johann,
L.
Harder,
E. K.
Wirth,
K.
Renko,
C. S.
Hoefig,
V.
Kracke,
J.
Hackler,
B.
Engelmann,
M.
Rauner,
J.
Kohrle,
L.
Schomburg,
G.
Homuth,
U.
Volker,
G.
Brabant, and
J.
Mittag,
CD5L Constitutes a Novel Biomarker for Integrated Hepatic Thyroid Hormone Action, Thyroid , vol. 30, no. 6, pp. 908-923, 2020.
CD5L Constitutes a Novel Biomarker for Integrated Hepatic Thyroid Hormone Action, Thyroid , vol. 30, no. 6, pp. 908-923, 2020.
| DOI: | 10.1089/thy.2019.0635 |
| Datei: | 32183611 |
B.
Herrmann,
L.
Harder,
R.
Oelkrug,
J.
Chen,
S.
Gachkar,
S.
Nock,
J.
Resch,
M.
Korkowski,
H.
Heuer, and
J.
Mittag,
Central Hypothyroidism Impairs Heart Rate Stability and Prevents Thyroid Hormone-Induced Cardiac Hypertrophy and Pyrexia, Thyroid , 2020.
Central Hypothyroidism Impairs Heart Rate Stability and Prevents Thyroid Hormone-Induced Cardiac Hypertrophy and Pyrexia, Thyroid , 2020.
| DOI: | 10.1089/thy.2019.0705 |
| Datei: | 32188347 |
S.
Mehl,
Q.
Sun,
C. L.
Gorlich,
J.
Hackler,
J. F.
Kopp,
K.
Renko,
J.
Mittag,
T.
Schwerdtle, and
L.
Schomburg,
Cross-sectional analysis of trace element status in thyroid disease, J Trace Elem Med Biol , vol. 58, pp. 126430, 2020.
Cross-sectional analysis of trace element status in thyroid disease, J Trace Elem Med Biol , vol. 58, pp. 126430, 2020.
| DOI: | 10.1016/j.jtemb.2019.126430 |
| Datei: | 31835129 |
F. M.
Raffaelli,
J.
Resch,
R.
Oelkrug,
K. A.
Iwen, and
J.
Mittag,
Dopamine receptor D1- and D2-agonists do not spark brown adipose tissue thermogenesis in mice, Sci Rep , vol. 10, no. 1, pp. 20203, 2020.
Dopamine receptor D1- and D2-agonists do not spark brown adipose tissue thermogenesis in mice, Sci Rep , vol. 10, no. 1, pp. 20203, 2020.
| DOI: | 10.1038/s41598-020-77143-6 |
| Datei: | 33214601 |
R.
Oelkrug,
C.
Krause,
B.
Herrmann,
J.
Resch,
S.
Gachkar,
A. T.
El Gammal,
S.
Wolter,
O.
Mann,
H.
Oster,
H.
Kirchner, and
J.
Mittag,
Maternal Brown Fat Thermogenesis Programs Glucose Tolerance in the Male Offspring, Cell Rep , vol. 33, no. 5, pp. 108351, 2020.
Maternal Brown Fat Thermogenesis Programs Glucose Tolerance in the Male Offspring, Cell Rep , vol. 33, no. 5, pp. 108351, 2020.
| DOI: | 10.1016/j.celrep.2020.108351 |
| Datei: | 33147454 |
J. Mittag,
More Than Fever - Novel Concepts in the Regulation of Body Temperature by Thyroid Hormones, Exp Clin Endocrinol Diabetes , vol. 128, no. 6-07, pp. 428-431, 2020.
More Than Fever - Novel Concepts in the Regulation of Body Temperature by Thyroid Hormones, Exp Clin Endocrinol Diabetes , vol. 128, no. 6-07, pp. 428-431, 2020.
| DOI: | 10.1055/a-1014-2510 |
| Datei: | 31652476 |
S.
Gachkar,
R.
Oelkrug,
B.
Herrmann,
T. S.
Scanlan,
Q.
Sun,
H.
Biebermann,
C. S.
Hoefig,
L.
Schomburg, and
J.
Mittag,
N- and O-Acetylated 3-Iodothyronamines Have No Metabolic or Thermogenic Effects in Male Mice, Eur Thyroid J , vol. 9, no. 2, pp. 57-66, 2020.
N- and O-Acetylated 3-Iodothyronamines Have No Metabolic or Thermogenic Effects in Male Mice, Eur Thyroid J , vol. 9, no. 2, pp. 57-66, 2020.
| DOI: | 10.1159/000504887 |
| Datei: | 32257954 |
R.
Dore,
R.
Krotenko,
J. P.
Reising,
L.
Murru,
S. M.
Sundaram,
A.
Di Spiezio,
H.
Muller-Fielitz,
M.
Schwaninger,
O.
Johren,
J.
Mittag,
M.
Passafaro,
M.
Shanabrough,
T. L.
Horvath,
A.S.
Schulz, and
H.
Lehnert,
Nesfatin-1 decreases the motivational and rewarding value of food, Neuropsychopharmacology , 2020.
Nesfatin-1 decreases the motivational and rewarding value of food, Neuropsychopharmacology , 2020.
| DOI: | 10.1038/s41386-020-0682-3 |
| Datei: | 32353862 |
S.
Nock,
C.
Hofig,
L.
Harder,
L.
Schomburg,
G.
Brabant, and
J.
Mittag,
Unraveling the Molecular Basis for Successful Thyroid Hormone Replacement Therapy: The Need for New Thyroid Tissue- and Pathway-Specific Biomarkers, Exp Clin Endocrinol Diabetes , vol. 128, no. 6-07, pp. 473-478, 2020.
Unraveling the Molecular Basis for Successful Thyroid Hormone Replacement Therapy: The Need for New Thyroid Tissue- and Pathway-Specific Biomarkers, Exp Clin Endocrinol Diabetes , vol. 128, no. 6-07, pp. 473-478, 2020.
| DOI: | 10.1055/a-1012-8484 |
| Datei: | 31590191 |
2019
K.
Johann,
A. L.
Cremer,
A. W.
Fischer,
M.
Heine,
E. R.
Pensado,
J.
Resch,
S.
Nock,
S.
Virtue,
L.
Harder,
R.
Oelkrug,
M.
Astiz,
G.
Brabant,
A.
Warner,
A.
Vidal-Puig,
H.
Oster,
A.
Boelen,
M.
Lopez,
J.
Heeren,
J. W.
Dalley,
H.
Backes, and
J.
Mittag,
Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption, Cell Rep , vol. 27, no. 11, pp. 3385-3400 e3, 2019.
Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption, Cell Rep , vol. 27, no. 11, pp. 3385-3400 e3, 2019.
| DOI: | 10.1016/j.celrep.2019.05.054 |
| Datei: | 31189119 |
S.
Gachkar,
S.
Nock,
C.
Geissler,
R.
Olkrug,
K.
Johann,
J.
Resch,
A.
Rahman,
A.
Arner,
H.
Kirchner, and
J.
Mittag,
Aortic Effects of Thyroid Hormone in Male Mice, J Mol Endocrinol , 2019.
Aortic Effects of Thyroid Hormone in Male Mice, J Mol Endocrinol , 2019.
| DOI: | 10.1530/JME-18-0217 |
| Datei: | 30608905 |
2018
J.
Braunig,
S.
Mergler,
S.
Jyrch,
C. S.
Hoefig,
M.
Rosowski,
J.
Mittag,
H.
Biebermann, and
N.
Khajavi,
3-Iodothyronamine Activates a Set of Membrane Proteins in Murine Hypothalamic Cell Lines, Front Endocrinol (Lausanne) , vol. 9, pp. 523, 2018.
3-Iodothyronamine Activates a Set of Membrane Proteins in Murine Hypothalamic Cell Lines, Front Endocrinol (Lausanne) , vol. 9, pp. 523, 2018.
| DOI: | 10.3389/fendo.2018.00523 |
| Datei: | 30298050 |
K.
Johann,
M. C.
Reis,
L.
Harder,
B.
Herrmann,
S.
Gachkar,
J.
Mittag, and
R.
Oelkrug,
Effects of sildenafil treatment on thermogenesis and glucose homeostasis in diet-induced obese mice, Nutr Diabetes , vol. 8, no. 1, pp. 9, 2018.
Effects of sildenafil treatment on thermogenesis and glucose homeostasis in diet-induced obese mice, Nutr Diabetes , vol. 8, no. 1, pp. 9, 2018.
| DOI: | 10.1038/s41387-018-0026-0 |
| Datei: | 29549244 |
L.
Harder,
N.
Schanze,
A.
Sarsenbayeva,
F.
Kugel,
J.
Kohrle,
L.
Schomburg,
J.
Mittag, and
C. S.
Hoefig,
In vivo Effects of Repeated Thyronamine Administration in Male C57BL/6J Mice, Eur Thyroid J , vol. 7, no. 1, pp. 3-12, 2018.
In vivo Effects of Repeated Thyronamine Administration in Male C57BL/6J Mice, Eur Thyroid J , vol. 7, no. 1, pp. 3-12, 2018.
| DOI: | 10.1159/000481856 |
| Datei: | 29594048 |
M.
Hirose,
P.
Schilf,
Y.
Gupta,
K.
Zarse,
A.
Kunstner,
A.
Fahnrich,
H.
Busch,
J.
Yin,
M. N.
Wright,
A.
Ziegler,
M.
Vallier,
M.
Belheouane,
J. F.
Baines,
D.
Tautz,
K.
Johann,
R.
Oelkrug,
J.
Mittag,
H.
Lehnert,
A.
Othman,
O.
Johren,
M.
Schwaninger,
C.
Prehn,
J.
Adamski,
K.
Shima,
J.
Rupp,
R.
Hasler,
G.
Fuellen,
R.
Kohling,
M.
Ristow, and
S. M.
Ibrahim,
Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice, Sci Rep , vol. 8, no. 1, pp. 5872, 2018.
Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice, Sci Rep , vol. 8, no. 1, pp. 5872, 2018.
| DOI: | 10.1038/s41598-018-24290-6 |
| Datei: | 29651131 |
L.
Harder,
S.
Dudazy-Gralla,
H.
Muller-Fielitz,
J.
Hjerling Leffler,
B.
Vennstrom,
H.
Heuer, and
J.
Mittag,
Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area, J Neuroendocrinol , vol. 30, no. 3, pp. e12573, 2018.
Maternal thyroid hormone is required for parvalbumin neurone development in the anterior hypothalamic area, J Neuroendocrinol , vol. 30, no. 3, pp. e12573, 2018.
| DOI: | 10.1111/jne.12573 |
| Datei: | 29377458 |
C.
Krause,
M.
Grohs,
A.
El Gammal,
S.
Wolter,
H.
Lehnert,
O.
Mann,
J.
Mittag, and
H.
Kirchner,
Reduced expression of thyroid hormone receptor beta in human nonalcoholic steatohepatitis, Endocr Connect , 2018.
Reduced expression of thyroid hormone receptor beta in human nonalcoholic steatohepatitis, Endocr Connect , 2018.
| DOI: | 10.1530/EC-18-0499 |
| Datei: | 30496129 |
J.
Braunig,
J.
Dinter,
C. S.
Hofig,
S.
Paisdzior,
M.
Szczepek,
P.
Scheerer,
M.
Rosowski,
J.
Mittag,
G.
Kleinau, and
H.
Biebermann,
The Trace Amine-Associated Receptor 1 Agonist 3-Iodothyronamine Induces Biased Signaling at the Serotonin 1b Receptor, Front Pharmacol , vol. 9, pp. 222, 2018.
The Trace Amine-Associated Receptor 1 Agonist 3-Iodothyronamine Induces Biased Signaling at the Serotonin 1b Receptor, Front Pharmacol , vol. 9, pp. 222, 2018.
| DOI: | 10.3389/fphar.2018.00222 |
| Datei: | 29593543 |
2017
N.
Schanze,
S. F.
Jacobi,
E.
Rijntjes,
S.
Mergler,
M.
Del Olmo,
C. S.
Hoefig,
N.
Khajavi,
I.
Lehmphul,
H.
Biebermann,
J.
Mittag, and
J.
Kohrle,
3-Iodothyronamine Decreases Expression of Genes Involved in Iodide Metabolism in Mouse Thyroids and Inhibits Iodide Uptake in PCCL3 Thyrocytes, Thyroid , vol. 27, no. 1, pp. 11-22, 2017.
3-Iodothyronamine Decreases Expression of Genes Involved in Iodide Metabolism in Mouse Thyroids and Inhibits Iodide Uptake in PCCL3 Thyrocytes, Thyroid , vol. 27, no. 1, pp. 11-22, 2017.
| DOI: | 10.1089/thy.2016.0182 |
| Datei: | 27788620 |
S.
Gachkar,
R.
Oelkrug,
N.
Martinez-Sanchez,
E.
Rial-Pensado,
A.
Warner,
C. S.
Hoefig,
M.
Lopez, and
J.
Mittag,
3-Iodothyronamine Induces Tail Vasodilation Through Central Action in Male Mice, Endocrinology , vol. 158, no. 6, pp. 1977-1984, 2017.
3-Iodothyronamine Induces Tail Vasodilation Through Central Action in Male Mice, Endocrinology , vol. 158, no. 6, pp. 1977-1984, 2017.
| DOI: | 10.1210/en.2016-1951 |
| Datei: | 28368510 |
R.
Oelkrug,
B.
Herrmann,
C.
Geissler,
L.
Harder,
C.
Koch,
H.
Lehnert,
H.
Oster,
H.
Kirchner, and
J.
Mittag,
Dwarfism and insulin resistance in male offspring caused by alpha1-adrenergic antagonism during pregnancy, Mol Metab , vol. 6, no. 10, pp. 1126-1136, 2017.
Dwarfism and insulin resistance in male offspring caused by alpha1-adrenergic antagonism during pregnancy, Mol Metab , vol. 6, no. 10, pp. 1126-1136, 2017.
| DOI: | 10.1016/j.molmet.2017.06.016 |
| Datei: | 29031714 |
N.
Martinez-Sanchez,
P.
Seoane-Collazo,
C.
Contreras,
L.
Varela,
J.
Villarroya,
E.
Rial-Pensado,
X.
Buque,
I.
Aurrekoetxea,
T. C.
Delgado,
R.
Vazquez-Martinez,
I.
Gonzalez-Garcia,
J.
Roa,
A. J.
Whittle,
B.
Gomez-Santos,
V.
Velagapudi,
Y. C. L.
Tung,
D. A.
Morgan,
P. J.
Voshol,
P. B.
Morentin,
T.
Lopez-Gonzalez,
L.
Linares-Pose,
F.
Gonzalez,
K.
Chatterjee,
T.
Sobrino,
G.
Medina-Gomez,
R. J.
Davis,
N.
Casals,
M.
Oresic,
A. P.
Coll,
A.
Vidal-Puig,
J.
Mittag,
M.
Tena-Sempere,
M. M.
Malagon,
C.
Dieguez,
M. L.
Martinez-Chantar,
P.
Aspichueta,
K.
Rahmouni,
R.
Nogueiras,
G.
Sabio,
F.
Villarroya, and
M.
Lopez,
Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance, Cell Metab , vol. 26, no. 1, pp. 212-229 e12, 2017.
Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance, Cell Metab , vol. 26, no. 1, pp. 212-229 e12, 2017.
| DOI: | 10.1016/j.cmet.2017.06.014 |
| Datei: | 28683288 |
H.
Muller-Fielitz,
M.
Stahr,
M.
Bernau,
M.
Richter,
S.
Abele,
V.
Krajka,
A.
Benzin,
J.
Wenzel,
K.
Kalies,
J.
Mittag,
H.
Heuer,
S.
Offermanns, and
M.
Schwaninger,
Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis, Nat Commun , vol. 8, no. 1, pp. 484, 2017.
Tanycytes control the hormonal output of the hypothalamic-pituitary-thyroid axis, Nat Commun , vol. 8, no. 1, pp. 484, 2017.
| DOI: | 10.1038/s41467-017-00604-6 |
| Datei: | 28883467 |
R.
Dore,
L.
Levata,
S.
Gachkar,
O.
Johren,
J.
Mittag,
H.
Lehnert, and
A.S.
Schulz,
The thermogenic effect of nesfatin-1 requires recruitment of the melanocortin system, J Endocrinol , vol. 235, no. 2, pp. 111-122, 2017.
The thermogenic effect of nesfatin-1 requires recruitment of the melanocortin system, J Endocrinol , vol. 235, no. 2, pp. 111-122, 2017.
| DOI: | 10.1530/JOE-17-0151 |
| Datei: | 28851749 |
